Amastatin

<strong>Amastatin</strong> <strong>Catalog number:</strong> MDP0464 <strong>CAS Number: </strong>120527-89-1 <strong>Sequence: </strong>[(2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl]-L-valyl-L-valyl-L-aspartic acid <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 474.4 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Quirk WS, Harding JW, Wright JW. Amastatin and bestatin-induced dipsogenicity in the Sprague-Dawley rat Brain Res Bull. 1987 Jul;19(1):145-7. 2: Aoyagi T, Tobe H, Kojima F, Hamada M, Takeuchi T, Umezawa H. Amastatin, an inhibitor of aminopeptidase A, produced by actinomycetes J Antibiot (Tokyo). 1978 Jun;31(6):636-8. 3: Meisenberg G, Simmons WH. Amastatin potentiates the behavioral effects of vasopressin and oxytocin in mice Peptides. 1984 May-Jun;5(3):535-9. 4: Oka T, Hiranuma T, Liu XF, Ohgiya N, Iwao K, Matsumiya T. [Enkephalin-inactivating enzymes] Nihon Yakurigaku Zasshi. 1993 Apr;101(4):197-207. 5: Chen X, Pittman QJ. Vasopressin and amastatin induce V(1)-receptor-mediated suppression of excitatory transmission in the rat parabrachial nucleus J Neurophysiol. 1999 Oct;82(4):1689-96. 6: Sullivan MJ, Beltz TG, Johnson AK. Amastatin potentiation of drinking induced by blood-borne angiotensin: evidence for mediation by endogenous brain angiotensin Brain Res. 1990 Mar 5;510(2):237-41. 7: Tobe H, Kojima F, Aoyagi T, Umezawa H. Purification by affinity chromatography using amastatin and properties of aminopeptidase A from pig kidney Biochim Biophys Acta. 1980 Jun 13;613(2):459-68. 8: Rich DH, Moon BJ, Harbeson S. Inhibition of aminopeptidases by amastatin and bestatin derivatives. Effect of inhibitor structure on slow-binding processes J Med Chem. 1984 Apr;27(4):417-22. 9: Patacchini R, Maggi CA. Amastatin interferes with the antagonist properties of MEN 10,208 in the rabbit pulmonary artery but not in the hamster trachea Eur J Pharmacol. 1993 May 12;236(1):31-7. <a href="https://pubmed.ncbi.nlm.nih.gov/2865258">10: Wilkes SH, Prescott JM. The slow, tight binding of bestatin and amastatin to aminopeptidases J Biol Chem. 1985 Oct 25;260(24):13154-62.</a> <br><strong>Products Related to Amastatin can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>