Boc-Pyr-OH

Boc-Pyr-OH is a Boc-protected pyroglutamic acid derivative. Boc-Pyr-OH stabilizes the amino group of pyroglutamic acid through the Boc protecting group, preventing unwanted reactions during peptide synthesis. Boc-Pyr-OH can be used in the research of thyrotropin-releasing hormone (TRH) synthesis[1].

Product Specifications

CAS Number

[53100-44-0]

Product Name Alternative

N-Boc-L-pyroglutamic acid

UNSPSC

12352200

Hazard Statement

H315, H319, H335

Target

Amino Acid Derivatives; Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/boc-pyr-oh.html

Purity

98.0

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(N1[C@H](C(O)=O)CCC1=O)OC(C)(C)C

Molecular Formula

C10H15NO5

Molecular Weight

229.23

Precautions

H315, H319, H335

References & Citations

[1]Okada Y, et al. Amino acids and peptides. Part 45. Development of a new N π-protecting group of histidine, N π- (1-adamantyloxymethyl) histidine, and its evaluation for peptide synthesis. Journal of the Chemical Society, Perkin Transactions 1, 1996 (17) : 2139-2143.