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Human ZNRF3 protein, His Tag (MALS verified)

Human ZNRF3, His Tag (ZN3-H52H3) is expressed from human 293 cells (HEK293) . It contains AA Lys 56 - Met 219 (Accession # Q9ULT6-1) .

Product Specifications

Background

The transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) is a negative feedback regulator of Wnt signalling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signalling by promoting the turnover of frizzled and LRP6 and acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.7 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q9ULT6-1

Expression Region

Lys 56 - Met 219

Host

HEK293

Target

ZNRF3

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

19.7 kDa

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

500ug*2

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/ZN3-H52H3.pdf

Species

Human

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