Bovine Alpha-Thrombin

<strong>Bovine Alpha-Thrombin</strong>_x000D_ <strong>Catalog number:</strong> B2013193_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1000 U_x000D_ <strong>Molecular Weight or Concentration:</strong> &gt; 1800 U/mg_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20° C_x000D_ <strong>Keywords:</strong> Bovine Alpha Thrombin_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lundblad RL, Nesheim ME, Straight DL, Sailor S, Bowie J, Jenzano JW, Roberts JD, Mann KG. Bovine alpha- and beta-thrombin. Reduced fibrinogen-clotting activity of beta-thrombin is not a consequence of reduced affinity for fibrinogen J Biol Chem. 1984 Jun 10;259(11):6991-5._x000D_ 2: Clark JA, Humphries JE, Crean S, Reynolds MW. Topical bovine thrombin: a 21-year review of topical bovine thrombin spontaneous case safety reports submitted to FDA's Adverse Event Reporting System Pharmacoepidemiol Drug Saf. 2010 Feb;19(2):107-14._x000D_ 3: Cahn J. Clinical Issues-October 2022 AORN J. 2022 Oct;116(4):359-367._x000D_ 4: Crean S, Michels SL, Moschella K, Reynolds MW. Bovine thrombin safety reporting: an example of study design and publication bias J Surg Res. 2010 Jan;158(1):77-86._x000D_ 5: Bishop PD, Lewis KB, Schultz J, Walker KM. Comparison of recombinant human thrombin and plasma-derived human alpha-thrombin Semin Thromb Hemost. 2006 Apr;32 Suppl 1:86-97._x000D_ 6: Crean SM, Michels SL, Reynolds MW. Exogenous bovine thrombin as a biomarker of exposure and outcome Expert Rev Mol Diagn. 2008 Sep;8(5):651-61._x000D_ 7: Ganesh V, Lee AY, Clardy J, Tulinsky A. Comparison of the structures of the cyclotheonamide A complexes of human alpha-thrombin and bovine beta-trypsin Protein Sci. 1996 May;5(5):825-35._x000D_ 8: Clark J, Crean S, Reynolds MW. Topical bovine thrombin and adverse events: a review of the literature Curr Med Res Opin. 2008 Jul;24(7):2071-87._x000D_ 9: He Zhu, Hoppensteadt D, Cunanan J, Fareed J. Cross-reactivity of rabbit anti-bovine thrombin IgGs with human alpha-thrombin and a recombinant version of human thrombin (Recothrom) Clin Appl Thromb Hemost. 2010 Jun;16(3):273-80._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/1517214">10: Vitali J, Martin PD, Malkowski MG, Robertson WD, Lazar JB, Winant RC, Johnson PH, Edwards BF. The structure of a complex of bovine alpha-thrombin and recombinant hirudin at 2.8-A resolution J Biol Chem. 1992 Sep 5;267(25):17670-8.</a>_x000D_ _x000D_ <strong>Products Related to Bovine Alpha-Thrombin can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>