Mephenytoin
Mephenytoin, an anticonvulsant, is the CYP2C19 and CYP2B6 substrate[1].
Product Specifications
CAS Number
[50-12-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mephenytoin.html
Purity
99.96
Solubility
DMSO : 50 mg/mL (ultrasonic; warming)
Smiles
O=C1N(C)C(C(C2=CC=CC=C2)(CC)N1)=O
Molecular Formula
C12H14N2O2
Molecular Weight
218.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Klaassen T, et al. Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity. Eur J Clin Pharmacol. 2008;64 (4) :387-398.|[2]D R Minck, et al. Comparison of the behavioral teratogenic potential of phenytoin, mephenytoin, ethotoin, and hydantoin in rats. Teratology. 1991 Apr;43 (4) :279-93. |[3]J H Maguire, et al. Hypolipidemic activity of antiepileptic 5-phenylhydantoins in mice. Eur J Pharmacol. 1985 Oct 29;117 (1) :135-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
CYP2
Available Sizes
Curated Selection
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