SARS-CoV-2 (COVID-19) S2 protein, His Tag
SARS-CoV-2 S2 protein, His Tag (S2N-C52H2) is expressed from human 293 cells (HEK293) .
Product Specifications
Background
It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 60.0 kDa. The protein migrates as 65-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
QHD43416.1
Expression Region
Ser 686 - Pro1213
Host
HEK293
Target
Spike S2
Conjugation
Unconjugated
Tag
C-10xHis
Source
SARS-CoV-2
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized SARS-CoV-2 S2 protein, His Tag (Cat. No. S2N-C52H2) at 0.2 μg/mL (100 ug/well) can bind Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4 (AS86) (Cat. No. S2N-S86) with a linear range of 1.5-2.5 ng/mL (QC tested).
Format
Liquid
Buffer
20 mM PB, 300 mM NaCl, pH7.4
Additives
Glycerol
Molecular Weight
60.0 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
100mg*1
Host or Source
HEK293
Species
SARS-CoV-2
Protein ID
QHD43416.1
Preservative
Glycerol
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