ZD-6888 (hydrochloride)
ZD-6888 hydrochloride (ICI-D 6888 hydrochloride) is an antagonist for angiotensin II, which competitively inhibits the angiotensin II-mediated release of renin, affects the renal structure and function[1].
Product Specifications
CAS Number
138620-17-4
Product Name Alternative
ICI-D 6888 (hydrochloride)
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/zd-6888-hydrochloride.html
Smiles
CCC1=NC2=C(CCCC2)C(OCC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)=C1.Cl
Molecular Formula
C25H26ClN5O
Molecular Weight
447.96
References & Citations
[1]Jackson DG, et al., Histopathological and ultrastructural changes in the juxtaglomerular apparatus of the rat following administration of ZENECA ZD6888 (2-ethyl-5,6,7,8-tetrahydro-4-[ (2'- (1H-tetrazol-5-yl) biphenyl-4-yl) - methoxy]quinoline), an angiotensin II antagonist. Toxicol Pathol. 1995 Jan-Feb;23 (1) :7-15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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