Isodunnianol

Isodunnianol is a autophagy inducer. Isodunnianol induces autophagy and increases he expression of pAMPK172, pULK1555, decreases teh expression of pULK1757, SQSTM2. Isodunnianol decreases Doxorubicin (HY-15142A) -induced cardiotoxicity[1].

Product Specifications

CAS Number

[139726-30-0]

UNSPSC

12352005

Target

Autophagy

Type

Natural Products

Related Pathways

Autophagy

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/isodunnianol.html

Solubility

10 mM in DMSO

Smiles

OC1=C(C2=CC(CC=C)=CC=C2O)C=C(CC=C)C=C1OC3=CC=C(CC=C)C=C3

Molecular Formula

C27H26O3

Molecular Weight

398.49

References & Citations

[1]Chen C , et al . Isodunnianol alleviates duxorubicin-induced myocardial injury by activating protective autophagy. Food Funct. 2019 May 22;10 (5) :2651-2657.