Isodunnianol
Isodunnianol is a autophagy inducer. Isodunnianol induces autophagy and increases he expression of pAMPK172, pULK1555, decreases teh expression of pULK1757, SQSTM2. Isodunnianol decreases Doxorubicin (HY-15142A) -induced cardiotoxicity[1].
Product Specifications
CAS Number
[139726-30-0]
UNSPSC
12352005
Target
Autophagy
Type
Natural Products
Related Pathways
Autophagy
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/isodunnianol.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C2=CC(CC=C)=CC=C2O)C=C(CC=C)C=C1OC3=CC=C(CC=C)C=C3
Molecular Formula
C27H26O3
Molecular Weight
398.49
References & Citations
[1]Chen C , et al . Isodunnianol alleviates duxorubicin-induced myocardial injury by activating protective autophagy. Food Funct. 2019 May 22;10 (5) :2651-2657.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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