SARS-CoV-2 Spike RBD Beta Variant

<strong>SARS-CoV-2 Spike RBD Beta Variant</strong>_x000D_ <strong>Catalog number:</strong> B2010499_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 27 kDa_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular component of many serological and antigenic assays for SARS-CoV-2 and its variants_x000D_ <strong>Storage:</strong> -20℃_x000D_ <strong>Keywords:</strong> Beta Variant Spike, B.1.351 Spike RBD, Beta RBD_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <a href="https://moleculardepot.com/wp-content/uploads/2022/03/MKT-010-SARS-CoV-2-Brochure-Rev-A.pdf"><strong>Download SARS-CoV-2 Brochure</strong></a>_x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Rattanapisit K, Bulaon CJI, Khorattanakulchai N, Shanmugaraj B, Wangkanont K,_x000D_ Phoolcharoen W. Plant-produced SARS-CoV-2 receptor binding domain (RBD) variants_x000D_ showed differential binding efficiency with anti-spike specific monoclonal_x000D_ antibodies. PLoS One. 2021 Aug 11;16(8):e0253574._x000D_ _x000D_ 2: Kim S, Liu Y, Lei Z, Dicker J, Cao Y, Zhang XF, Im W. Differential_x000D_ Interactions Between Human ACE2 and Spike RBD of SARS-CoV-2 Variants of Concern._x000D_ bioRxiv [Preprint]. 2021 Jul 26:2021.07.23.453598._x000D_ _x000D_ 3: Peters MH, Bastidas O, Kokron DS, Henze CE. Transformations, Lineage_x000D_ Comparisons, and Analysis of Down to Up Protomer States of Variants of the SARS-_x000D_ CoV-2 Prefusion Spike Protein Including the UK Variant B.1.1.7. bioRxiv_x000D_ [Preprint]. 2021 Apr 2:2021.02.09.430519._x000D_ _x000D_ 4: Trigueiro-Louro J, Correia V, Figueiredo-Nunes I, Gíria M, Rebelo-de-Andrade_x000D_ H. Unlocking COVID therapeutic targets: A structure-based rationale against_x000D_ SARS-CoV-2, SARS-CoV and MERS-CoV Spike. Comput Struct Biotechnol J. 2020 Jul_x000D_ 31;18:2117-2131._x000D_ _x000D_ 5: Jawad B, Adhikari P, Podgornik R, Ching WY. Key Interacting Residues between_x000D_ RBD of SARS-CoV-2 and ACE2 Receptor: Combination of Molecular Dynamics_x000D_ Simulation and Density Functional Calculation. J Chem Inf Model. 2021 Aug_x000D_ 24:acs.jcim.1c00560._x000D_ _x000D_ 6: Zahradník J, Marciano S, Shemesh M, Zoler E, Harari D, Chiaravalli J, Meyer_x000D_ B, Rudich Y, Li C, Marton I, Dym O, Elad N, Lewis MG, Andersen H, Gagne M, Seder_x000D_ RA, Douek DC, Schreiber G. SARS-CoV-2 variant prediction and antiviral drug_x000D_ design are enabled by RBD in vitro evolution. Nat Microbiol. 2021_x000D_ Sep;6(9):1188-1198._x000D_ _x000D_ 7: Ou J, Zhou Z, Dai R, Zhang J, Zhao S, Wu X, Lan W, Ren Y, Cui L, Lan Q, Lu L,_x000D_ Seto D, Chodosh J, Wu J, Zhang G, Zhang Q. V367F Mutation in SARS-CoV-2 Spike_x000D_ RBD Emerging during the Early Transmission Phase Enhances Viral Infectivity_x000D_ through Increased Human ACE2 Receptor Binding Affinity. J Virol. 2021 Jul_x000D_ 26;95(16):e0061721._x000D_ _x000D_ 8: Mohammadi M, Shayestehpour M, Mirzaei H. The impact of spike mutated variants_x000D_ of SARS-CoV2 [Alpha, Beta, Gamma, Delta, and Lambda] on the efficacy of subunit_x000D_ recombinant vaccines. Braz J Infect Dis. 2021 Aug 17;25(4):101606._x000D_ _x000D_ 9: Barton MI, MacGowan SA, Kutuzov MA, Dushek O, Barton GJ, van der Merwe PA._x000D_ Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand the human_x000D_ ACE2 receptor on binding affinity and kinetics. Elife. 2021 Aug 26;10:e70658._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34388530/">10: Tsai MS, Yang YH, Lin YS, Chang GH, Hsu CM, Yeh RA, Shu LH, Cheng YC, Liu_x000D_ HT, Wu YH, Wu YH, Shen RC, Wu CY. GB-2 blocking the interaction between ACE2 and_x000D_ wild type and mutation of spike protein of SARS-CoV-2. Biomed Pharmacother. 2021_x000D_ Aug 5;142:112011. </a>_x000D_ _x000D_ <strong>Products Related to SARS-CoV-2 Spike RBD Beta Variant</strong> <a href="https://moleculardepot.com/product-category/SARS-CoV-2/">: SARS-CoV-2</a>