Benzylideneacetone

Benzylideneacetone (Benzalacetone) is an orally active antibiotic, tyrosinase inhibitor, phospholipase A2 inhibitor, and immunosuppressant. Benzylideneacetone has antibacterial activity against some gram-negative plant-pathogenic bacteria. Benzylideneacetone can also be used in the synthesis of chemicals and drugs, and as a flavoring additive for some foods[1][2][3].

Product Specifications

CAS Number

[122-57-6]

Product Name Alternative

Benzalacetone

UNSPSC

12352005

Hazard Statement

H315, H317

Target

Antibiotic; Bacterial; Endogenous Metabolite; Phospholipase; Tyrosinase

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/benzylideneacetone-1.html

Concentration

10mM

Purity

99.66

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(/C=C/C1=CC=CC=C1)=O

Molecular Formula

C10H10O

Molecular Weight

146.19

Precautions

H315, H317

References & Citations

[1]Ji D, et al. Identification of an antibacterial compound, benzylideneacetone, from Xenorhabdus nematophila against major plant-pathogenic bacteria. FEMS Microbiol Lett. 2004 Oct 15;239 (2) :241-8.|[2]Liu X, et al. Inhibition effects of benzylideneacetone, benzylacetone, and 4-phenyl-2-butanol on the activity of mushroom tyrosinase. J Biosci Bioeng. 2015 Mar;119 (3) :275-9.|[3]Kwon B, et al. Benzylideneacetone, an immunosuppressant, enhances virulence of Bacillus thuringiensis against beet armyworm (Lepidoptera: Noctuidae) . J Econ Entomol. 2008 Feb;101 (1) :36-41.