Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

BHPI

BHPI is a nuclear receptor ERα inhibitor. BHPI activates PLCγ and UPR. BHPI has antitumor activity against breast, endometrial, and ovarian cancers[1][2].

Product Specifications

CAS Number

[56632-39-4]

UNSPSC

12352005

Target

Estrogen Receptor/ERR; Phospholipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/BHPI.html

Purity

98.0

Solubility

DMSO : 120 mg/mL (ultrasonic)

Smiles

O=C1NC2=C(C=CC=C2C)C1(C3=CC=C(O)C=C3)C4=CC=C(O)C=C4

Molecular Formula

C21H17NO3

Molecular Weight

331.36

References & Citations

[1]Andruska ND, et al. Estrogen receptor α inhibitor activates the unfolded protein response, blocks protein synthesis, and induces tumor regression. Proc Natl Acad Sci U S A. 2015 Apr 14;112 (15) :4737-42.|[2]Mao C, et al. Antiestrogen Resistant Cell Lines Expressing Estrogen Receptor α Mutations Upregulate the Unfolded Protein Response and are Killed by BHPI. Sci Rep. 2016 Oct 7;6:34753.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-12825/BHPI-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-12825/BHPI-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SOX15 Antibody
GWB-ML565G 50 µg

SOX15 Antibody

Ask
View Details
HLA-DQ (MHC II) Mouse Monoclonal Antibody
MBS439067-01 0.02 mg (With BSA & Azide at 0.2mg/mL)

HLA-DQ (MHC II) Mouse Monoclonal Antibody

Ask
View Details
HLA-DQ (MHC II) Mouse Monoclonal Antibody
MBS439067-02 0.1 mg (With BSA & Azide at 0.2mg/mL)

HLA-DQ (MHC II) Mouse Monoclonal Antibody

Ask
View Details
HLA-DQ (MHC II) Mouse Monoclonal Antibody
MBS439067-03 0.1 mg (Without BSA & Azide at 1mg/mL)

HLA-DQ (MHC II) Mouse Monoclonal Antibody

Ask
View Details
HLA-DQ (MHC II) Mouse Monoclonal Antibody
MBS439067-04 5x 0.1 mg (With BSA & Azide at 0.2mg/mL)

HLA-DQ (MHC II) Mouse Monoclonal Antibody

Ask
View Details
HLA-DQ (MHC II) Mouse Monoclonal Antibody
MBS439067-05 5x 0.1 mg (Without BSA & Azide at 1mg/mL)

HLA-DQ (MHC II) Mouse Monoclonal Antibody

Ask
View Details