ICI 186756
ICI 186756 is a compound that inhibits the activity of human neutrophil elastase, has a competitive inhibitory effect on the enzyme, can inhibit enzyme-induced lung changes, and can also modulate hamster lung lesions.
Product Specifications
CAS Number
95500-67-7
UNSPSC
12352005
Target
Elastase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ici-186756.html
Smiles
O=C(N[C@H](C=O)C(C)C)[C@H]1N(C([C@H](C(C)C)NC([C@H](CCCCNC(OCC2=CC=CC=C2)=O)NC(CCC(O)=O)=O)=O)=O)CCC1
Molecular Formula
C33H49N5O9
Molecular Weight
659.77
References & Citations
[1]Biochemical and pharmacological characterization of ICI 186,756: a novel, potent, and selective inhibitor of human neutrophil elastase
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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