DY-46-2
Product Specifications
UNSPSC Description
DY-46-2 is a high potency and selectivity novel non-nucleoside DNA methyltransferase 3A (DNMT3A) inhibitor with an IC50 value of 0.39 μM[1].
Target Antigen
DNA Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dy-46-2.html
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C)OC(N=CN2CCN3CCCC3)=C1C2=O)NC4=CC=C(S(=O)(N)=O)N=C4
Molecular Weight
446.48
References & Citations
[1]J. Yu, et al. Discovery of novel non-nucleoside inhibitors with high potency andselectivity for DNA methyltransferase 3A. European Journal of Medicinal Chemistry (2022).
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151136/DY-46-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151136/DY-46-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1105110-83-5
Available Sizes
Curated Selection
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