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Des-​Gln14-​Ghrelin

Des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a) . des-Gln14-ghrelin potently induces increases in [Ca2+]i in CHO-GHSR62 cells, with an EC50 of 2.4 nM[1].

Product Specifications

CAS Number

[293735-04-3]

UNSPSC

12352209

Target

GHSR

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/des-gln14-ghrelin.html

Purity

99.66

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N2[C@@H](CCC2)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)[C@H]3N(CCC3)C([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H]4N(CCC4)C([C@H](CO)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](COC(CCCCCCC)=O)NC([C@H](CO)NC(CN)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)CC6=CN=CN6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C142H237N43O40

Molecular Weight

3186.67

References & Citations

[1]H Hosoda, et al. Purification and Characterization of Rat des-Gln14-Ghrelin, a Second Endogenous Ligand for the Growth Hormone Secretagogue Receptor. J Biol Chem. 2000 Jul 21;275 (29) :21995-2000.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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