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4,5-DiHDPA lactone

4,5-DiHDPA lactone (5), a derivative of docosahexaenoic acid (DHA), is a PPARγ activator[1].

Product Specifications

CAS Number

[845673-68-9]

UNSPSC

12352005

Hazard Statement

H225-H319

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/4-5-dihdpa-lactone.html

Solubility

10 mM in DMSO

Smiles

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC(C1CCC(O1)=O)O

Molecular Formula

C22H32O3

Molecular Weight

344.49

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

References & Citations

[1]Keiko Yamamoto, et al. Identification of putative metabolites of docosahexaenoic acid as potent PPARgamma agonists and antidiabetic agents. Bioorg Med Chem Lett. 2005 Feb 1;15 (3) :517-22.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PPARγ

Available Sizes

Curated Selection

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