Fas Ligand (FasL), Human (Highly Pure)

<strong>Fas Ligand (FasL), Human (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2018483_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> ~34 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> FasL_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Muraki M, Honda S. Efficient production of human Fas receptor extracellular domain-human IgG1 heavy chain Fc domain fusion protein using baculovirus/silkworm expression system Protein Expr Purif. 2010 Oct;73(2):209-16._x000D_ 2: Berg M, Lundqvist A, McCoy P Jr, Samsel L, Fan Y, Tawab A, Childs R. Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells Cytotherapy. 2009;11(3):341-55._x000D_ 3: Vermijlen D, Luo D, Froelich CJ, Medema JP, Kummer JA, Willems E, Braet F, Wisse E. Hepatic natural killer cells exclusively kill splenic/blood natural killer-resistant tumor cells by the perforin/granzyme pathway J Leukoc Biol. 2002 Oct;72(4):668-76._x000D_ 4: Shan ZG, Zhao YL, Zhang JY, Yan ZB, Wang TT, Mao FY, Teng YS, Peng LS, Chen WY, Wang P, Cheng P, Tian WQ, Chen J, Chen W, Zhuang Y. FasL(+) PD-L2(+) Identifies a Novel Immunosuppressive Neutrophil Population in Human Gastric Cancer That Promotes Disease Progression Adv Sci (Weinh). 2022 Feb;9(5):e2103543._x000D_ 5: Lee HO, Ferguson TA. Biology of FasL Cytokine Growth Factor Rev. 2003 Jun-Aug;14(3-4):325-35._x000D_ 6: Regis S, Dondero A, Spaggiari GM, Serra M, Caliendo F, Bottino C, Castriconi R. miR-24-3p down-regulates the expression of the apoptotic factors FasL and BIM in human natural killer cells Cell Signal. 2022 Oct;98:110415._x000D_ 7: Zheng SY, Li DC, Zhang ZD, Zhao J, Ge JF. Adenovirus-mediated FasL gene transfer into human gastric carcinoma World J Gastroenterol. 2005 Jun 14;11(22):3446-50._x000D_ 8: Wu J, Richards MH, Huang J, Al-Harthi L, Xu X, Lin R, Xie F, Gibson AW, Edberg JC, Kimberly RP. Human FasL gene is a target of β-catenin/T-cell factor pathway and complex FasL haplotypes alter promoter functions PLoS One. 2011;6(10):e26143._x000D_ 9: Iwaniuk A, Grubczak K, Ratajczak-Wrona W, Garley M, Nowak K, Jabłońska E. N-nitrosodimethylamine (NDMA) induced apoptosis dependent on Fas/FasL complex in human leukocytes Hum Exp Toxicol. 2019 May;38(5):578-587._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/23801893">10: Liu ZH, Sun Z, Wang HQ, Ge J, Jiang TS, Chen YF, Ma Y, Wang C, Hu S, Samartzis D, Luo ZJ. FasL expression on human nucleus pulposus cells contributes to the immune privilege of intervertebral disc by interacting with immunocytes Int J Med Sci. 2013 Jun 21;10(8):1053-60. </a>_x000D_ _x000D_ <strong>Products Related to Fas Ligand (FasL), Human (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>