EGFR-IN-106
Product Specifications
UNSPSC Description
EGFR-IN-106 (compound 6) is a potentEGFR inhibitor with an IC50 value of 0.2396 µM. EGFR-IN-106 shows cytotoxic and anti-inflammatory activity[1]。
Target Antigen
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-106.html
Solubility
10 mM in DMSO
Smiles
NC1=NC2=CC=C(NC(CCN)=O)C=C2C(NC([C@H](C3=CC=C(CC(C)C)C=C3)C)=O)=N1
Molecular Weight
434.53
References & Citations
[1]Garduño-Villavicencio LR, et al. Compounds Consisting of Quinazoline, Ibuprofen, and Amino Acids with Cytotoxic and Anti-Inflammatory Effects. ChemMedChem. 2024 Feb 14:e202300651.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162323/EGFR-IN-106-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162323/
Clinical Information
No Development Reported
Curated Selection
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