EGFR-IN-106
EGFR-IN-106 (compound 6) is a potent EGFR inhibitor with an IC50 value of 0.2396 μM. EGFR-IN-106 shows cytotoxic and anti-inflammatory activity[1].
Product Specifications
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-106.html
Solubility
10 mM in DMSO
Smiles
NC1=NC2=CC=C(NC(CCN)=O)C=C2C(NC([C@H](C3=CC=C(CC(C)C)C=C3)C)=O)=N1
Molecular Formula
C24H30N6O2
Molecular Weight
434.53
References & Citations
[1]Garduño-Villavicencio LR, et al. Compounds Consisting of Quinazoline, Ibuprofen, and Amino Acids with Cytotoxic and Anti-Inflammatory Effects. ChemMedChem. 2024 Feb 14:e202300651.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1
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