Convallatoxin (Standard)
Convallatoxin (Standard) is the analytical standard of Convallatoxin. This product is intended for research and analytical applications. Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin ameliorates colitic inflammation via activation of PPARγ and suppression of NF-κB. Convallatoxin is a P-glycoprotein (P-gp) substrate and recognized Val982 as an important amino acid involved in its transport. Convallatoxin is an enhancer of ligand-induced MOR endocytosis with high potency and efficacy. Anti-inflammatory and anti-proliferative properties[1][2][3].
Product Specifications
CAS Number
508-75-8
UNSPSC
12352005
Target
NF-κB; P-glycoprotein; PPAR; Reference Standards
Type
Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/convallatoxin-standard.html
Smiles
O=C1OCC([C@H]2CC[C@]3(O)[C@]4([H])CC[C@]5(O)C[C@@H](O[C@H]6[C@@H]([C@@H]([C@H]([C@H](C)O6)O)O)O)CC[C@]5(C=O)[C@@]4([H])CC[C@]23C)=C1
Molecular Formula
C29H42O10
Molecular Weight
550.64
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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