Human Adenine Phosphoribosyltransferase (APRT)

<strong>Human Adenine Phosphoribosyltransferase (APRT)</strong>_x000D_ <strong>Catalog number:</strong> B2015619_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 19.6 kDa (180 aa)_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> AMP, APRTD, AMP diphosphorylase, Transphosphoribosidase_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Edvardsson VO, Sahota A, Palsson R. Adenine Phosphoribosyltransferase Deficiency 2012 Aug 30 [updated 2019 Sep 26]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(®) [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024._x000D_ 2: Bollée G, Harambat J, Bensman A, Knebelmann B, Daudon M, Ceballos-Picot I. Adenine phosphoribosyltransferase deficiency Clin J Am Soc Nephrol. 2012 Sep;7(9):1521-7._x000D_ 3: Young GH, Lin JT, Cheng YF, Ho CF, Kuok QY, Hsu RC, Liao WR, Chen CC, Chen HM. Modulation of adenine phosphoribosyltransferase-mediated salvage pathway to accelerate diabetic wound healing FASEB J. 2021 Mar;35(3):e21296._x000D_ 4: Silva CH, Silva M, Iulek J, Thiemann OH. Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism J Biomol Struct Dyn. 2008 Jun;25(6):589-97._x000D_ 5: Fratini A, Simmers RN, Callen DF, Hyland VJ, Tischfield JA, Stambrook PJ, Sutherland GR. A new location for the human adenine phosphoribosyltransferase gene (APRT) distal to the haptoglobin (HP) and fra(16)(q23)(FRA16D) loci Cytogenet Cell Genet. 1986;43(1-2):10-3._x000D_ 6: Glockzin K, Meek TD, Katzfuss A. Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: Only one of the two isoforms is kinetically active PLoS Negl Trop Dis. 2022 Feb 1;16(2):e0009926._x000D_ 7: Amundson SA, Fortunato JE, Liber HL. Heritable alterations at the adenine phosphoribosyltransferase (APRT) locus in human lymphoblastoid cell lines Mutat Res. 1992 Dec 16;284(2):287-95._x000D_ 8: Runolfsdottir HL, Palsson R, Agustsdottir IM, Indridason OS, Edvardsson VO. Kidney Disease in Adenine Phosphoribosyltransferase Deficiency Am J Kidney Dis. 2016 Mar;67(3):431-8._x000D_ 9: Kahan B, Held KR, DeMars R. The locus for human adenine phosphoribosyltransferase on chromosome no. 16 Genetics. 1974 Dec;78(4):1143-56._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15196008">10: Silva M, Silva CH, Iulek J, Thiemann OH. Three-dimensional structure of human adenine phosphoribosyltransferase and its relation to DHA-urolithiasis Biochemistry. 2004 Jun 22;43(24):7663-71. </a>_x000D_ _x000D_ <strong>Products Related to Human Adenine Phosphoribosyltransferase (APRT) can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>