Sugiol
Sugiol is an abietane diterpenoid, can be isolated from Calocedrus formosana bark. Sugiol has anti-inflammatory activity, could effectively reduce intracellular reactive oxygen species (ROS) production in lipopolysaccharide (LPS) -stimulated macrophages[1].
Product Specifications
CAS Number
[511-05-7]
Product Name Alternative
(+) -Sugiol; 10-Deoxoxanthoperol
UNSPSC
12352005
Target
ERK; Interleukin Related; JNK; p38 MAPK; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sugiol.html
Purity
99.88
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C=C(O)C(C(C)C)=C2)[C@@]3(C)CCCC(C)(C)[C@]3([H])C1
Molecular Formula
C20H28O2
Molecular Weight
300.44
References & Citations
[1]Chao KP, et al. Anti-inflammatory activity of sugiol, a diterpene isolated from Calocedrus formosana bark. Planta Med. 2005 Apr;71 (4) :300-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
ERK1; ERK2; IL-1; JNK1; JNK2; p38 MAPK
Available Sizes
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