Human BCAR1 Protein

<strong>Human BCAR1 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011624_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 500 µg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> breast cancer anti-estrogen resistance 1 protein, CAS protein, CAS1 protein, CASS1 protein, CRKAS protein, P130Cas protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Camacho Leal Mdel P, Sciortino M, Tornillo G, Colombo S, Defilippi P, Cabodi S. p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis Gene. 2015 May 10;562(1):1-7._x000D_ 2: Fang Y, Yan C, Zhao Q, Xu J, Liu Z, Gao J, Zhu H, Dai Z, Wang D, Tang D. The roles of microbial products in the development of colorectal cancer: a review Bioengineered. 2021 Dec;12(1):720-735._x000D_ 3: Brinkman A, van der Flier S, Kok EM, Dorssers LC. BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells J Natl Cancer Inst. 2000 Jan 19;92(2):112-20._x000D_ 4: Grebenchtchikov N, Brinkman A, van Broekhoven SP, de Jong D, Geurts-Moespot A, Span PN, Peters HA, Portengen H, Foekens JA, Sweep CG, Dorssers LC. Development of an ELISA for measurement of BCAR1 protein in human breast cancer tissue Clin Chem. 2004 Aug;50(8):1356-63._x000D_ 5: Huang W, Deng B, Wang RW, Tan QY, He Y, Jiang YG, Zhou JH. BCAR1 protein plays important roles in carcinogenesis and predicts poor prognosis in non-small-cell lung cancer PLoS One. 2012;7(4):e36124._x000D_ 6: van der Flier S, van der Kwast TH, Claassen CJ, Timmermans M, Brinkman A, Henzen-Logmans SC, Foekens JA, Dorssers LC. Immunohistochemical study of the BCAR1/p130Cas protein in non-malignant and malignant human breast tissue Int J Biol Markers. 2001 Jul-Sep;16(3):172-8._x000D_ 7: Yang F, Tanasa B, Micheletti R, Ohgi KA, Aggarwal AK, Rosenfeld MG. Shape of promoter antisense RNAs regulates ligand-induced transcription activation Nature. 2021 Jul;595(7867):444-449._x000D_ 8: Mao CG, Jiang SS, Wang XY, Tao SL, Jiang B, Mao CY, Yang YL, Hu ZY, Long T, Jin H, Tan QY, Huang Y, Deng B. BCAR1 plays critical roles in the formation and immunoevasion of invasive circulating tumor cells in lung adenocarcinoma Int J Biol Sci. 2021 Jun 11;17(10):2461-2475._x000D_ 9: van der Flier S, Brinkman A, Look MP, Kok EM, Meijer-van Gelder ME, Klijn JG, Dorssers LC, Foekens JA. Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment J Natl Cancer Inst. 2000 Jan 19;92(2):120-7._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33001583">10: Mao CG, Jiang SS, Shen C, Long T, Jin H, Tan QY, Deng B. BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A Thorac Cancer. 2020 Nov;11(11):3326-3336. </a>_x000D_ _x000D_ <strong>Products Related to Human BCAR1 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>