Ac-DMQD-CHO
Ac-DMQD-CHO is a selective inhibitor for caspase 3, with IC50 of 39 nM. Ac-DMQD-CHO reduces apoptosis, and exhibits neuroprotective efficacy[1].
Product Specifications
CAS Number
259199-63-8
UNSPSC
12352209
Target
Apoptosis; Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ac-dmqd-cho.html
Solubility
10 mM in DMSO
Smiles
OC(C[C@H](NC(C)=O)C(N[C@@H](CCSC)C(N[C@@H](CCC(N)=O)C(N[C@H](C=O)CC(O)=O)=O)=O)=O)=O
Molecular Formula
C20H31N5O10S
Molecular Weight
533.55
References & Citations
[1]Nuttall ME, et al., Inhibition of caspase-3-like activity prevents apoptosis while retaining functionality of human chondrocytes in vitro. J Orthop Res. 2000 May;18 (3) :356-63.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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