HNS-32
HNS-32 is a compound with antiarrhythmic and vasodilatory effects in canine hearts, showing superior protective effects against ischemic and reperfusion arrhythmias compared to an equivalent dose of Mexiletine hydrochloride. Furthermore, HNS-32 exhibits significant negative chronotropic effects on mammalian ventricular myocardium, indicating its potential application value in the study of acute coronary syndrome[1].
Product Specifications
CAS Number
186086-10-2
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hns-32.html
Smiles
CC1=C2C(/C(N(C)C)=N\CC3=NC=CC=C3)=CC(C)=C2C=C(C(C)C)C=C1
Molecular Formula
C24H29N3
Molecular Weight
359.51
References & Citations
[1]Saitoh, et al. "Effects of HNS-32, a novel antiarrhythmic drug, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats." Molecular and Cellular Biochemistry 205 (2000) : 133-140.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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