Nav1.8-IN-12
Nav1.8-IN-12 (Compound 23 R) is a Nav1.8 channel inhibitor. Nav1.8-IN-12 can be used in the study of pain-related diseases[1].
Product Specifications
CAS Number
[3029020-84-3]
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nav1-8-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC([S@@](=N)(C)=O)=C(F)C=C1)C2=C(OC3=CC=C(F)C=C3C)C=C(C(F)(F)F)C(Cl)=C2
Molecular Formula
C22H16ClF5N2O3S
Molecular Weight
518.88
References & Citations
[1]Daiguo Deng, et al. Compound as voltage-gated sodium channel inhibitor. WO2024032774A1.2024-02-15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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