Oxaceprol

Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis[1][2].

Product Specifications

CAS Number

[33996-33-7]

Product Name Alternative

N-Acetyl-L-hydroxyproline

UNSPSC

12352209

Hazard Statement

H318

Target

Amino Acid Derivatives

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Oxaceprol.html

Concentration

10mM

Purity

99.70

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(O)[C@H]1N(C(C)=O)C[C@H](O)C1

Molecular Formula

C7H11NO4

Molecular Weight

173.17

Precautions

H318

References & Citations

[1]Ionac M et al. Oxaceprol, an atypical inhibitor of inflammation and joint damage. Pharmacol Res, 1996 Jun, 33 (6) :367-73.|[2]Harpreet Singh Pawar, et al. Comparative evaluation of therapeutic efficacy of intra-articular oxaceprol with conventional modalities in osteoarthritis animal model. Clin Rheumatol. 2018 Aug;37 (8) :2195-2201.|[3]M Ionac, et al. Oxaceprol, an atypical inhibitor of inflammation and joint damage. Pharmacol Res. 1996 Jun;33 (6) :367-73.|[4]M J Parnham, et al. Antirheumatic agents and leukocyte recruitment. New light on the mechanism of action of oxaceprol. Biochem Pharmacol. 1999 Jul 15;58 (2) :209-15.