Propargyl-PEG4-Tos
Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1][2]. Propargyl-PEG4-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
875770-32-4
UNSPSC
12352203
Hazard Statement
H315, H319
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/propargyl-peg4-tos.html
Purity
99.25
Solubility
10 mM in DMSO
Smiles
C#CCOCCOCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O
Molecular Formula
C18H26O7S
Molecular Weight
386.46
Precautions
H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; PEG Linkers
Available Sizes
Frequently Asked Questions
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