CL-A3-7
CL-A3-7 is a virus-cell fusion inhibitor targeting the RSV F protein. It exerts its effect by blocking the interaction between the virus and the host IGF1R, effectively inhibiting infections of both wild-type RSV and the K394R variant. It is applicable to anti-RSV drug development and resistance-related research[1].
Product Specifications
CAS Number
2763661-39-6
UNSPSC
12352101
Target
IGF-1R; RSV
Type
Reference compound
Related Pathways
Anti-infection; Protein Tyrosine Kinase/RTK
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cl-a3-7.html
Smiles
FC1=CC=C(/C=C/C(N[C@@H]2[C@@H](O)CCC[C@H]2NC(/C=C/C3=CC=C(F)C=C3Br)=O)=O)C(Br)=C1
Molecular Formula
C24H22Br2F2N2O3
Molecular Weight
584.25
References & Citations
[1]Song Q, et al. A new mechanism of respiratory syncytial virus entry inhibition by small-molecule to overcome K394R-associated resistance. mBio. 2024 Sep 11;15 (9) :e0138524.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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