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Rabbit RNASEH2A Antibody

RNASEH2A is the catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. RNASEH2A participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication

Product Specifications

Product Name Alternative

AGS4; aicardi-Goutieres syndrome 4 protein; JUNB; ribonuclease H2 subunit A; ribonuclease H2, large subunit; ribonuclease HI large subunit; ribonuclease HI subunit A; RNase H (35) ; RNase H2 subunit A; RNase HI large subunit; RNASEHI; RNHIA; RNHL; THSD8

UniProt

O75792

Reactivity

Human

Immunogen

Between 250-300aa

Target

RNASEH2A

Clonality

Polyclonal

Conjugation

Unconjugated

Purification

Antigen Affinity Purified

Concentration

1000 μg/ml

Dilution

WB - 1:2,000 - 1:10,000; IP - 2 - 10 μg/mg lysate

Purity

Antigen Affinity Purified

Form

Liquid

Storage Conditions

2 - 8°C

Notes

For research use only.

Applications Notes

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight. Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody. Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate with 5% Normal Pig Serum added to the blocking buffer.

Tested Applications

IP, WB

NCBI Accession Number

NP_006388.2

Host or Source

Rabbit

Preservative

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Isotype

Whole IgG

Available Sizes

Frequently Asked Questions

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