Balamapimod
Balamapimod (MKI 833) is a reversible Ras/Raf/MEK inhibitor with potential anti-tumor activity.
Product Specifications
CAS Number
[863029-99-6]
Product Name Alternative
MKI 833
UNSPSC
12352005
Target
MEK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MKI_833.html
Purity
99.47
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#CC1=C(NC2=CC=C(SC3=NC=CN3C)C(Cl)=C2)C4=CC(OC)=C(N5CCC(N6CCCC6)CC5)C=C4N=C1
Molecular Formula
C30H32ClN7OS
Molecular Weight
574.14
References & Citations
[1]Jose R. Conejo-Garcia, et al. Methods and compositions for treatment of metastatic and refractory cancers and tumors. US20170020964A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MEK
Available Sizes
Curated Selection
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