Bergamottin (Standard)
Bergamottin (Standard) is the analytical standard of Bergamottin. This product is intended for research and analytical applications. Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM.
Product Specifications
CAS Number
7380-40-7
Product Name Alternative
5-Geranoxypsoralen (Standard) ; Bergamotine (Standard) ; Bergaptin (Standard)
UNSPSC
12352005
Target
Cytochrome P450; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bergamottin-standard.html
Smiles
O=C1C=CC2=C(OC/C=C(C)/CC/C=C(C)/C)C3=C(OC=C3)C=C2O1
Molecular Formula
C21H22O4
Molecular Weight
338.40
References & Citations
[1]Olguín-Reyes S, et al. Bergamottin is a competitive inhibitor of CYP1A1 and is antimutagenic in the Ames test. Food Chem Toxicol. 2012 Sep;50 (9) :3094-9.|[2]Wu HJ, et al. Bergamottin isolated from Citrus bergamia exerts in vitro and in vivo antitumor activity in lung adenocarcinoma through the induction of apoptosis, cell cycle arrest, mitochondrial membrane potential loss and inhibition of cell migration and invasion. Oncol Rep. 2016 Jul;36 (1) :324-32.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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