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Bergamottin (Standard)

Bergamottin (Standard) is the analytical standard of Bergamottin. This product is intended for research and analytical applications. Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM.

Product Specifications

CAS Number

7380-40-7

Product Name Alternative

5-Geranoxypsoralen (Standard) ; Bergamotine (Standard) ; Bergaptin (Standard)

UNSPSC

12352005

Target

Cytochrome P450; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bergamottin-standard.html

Smiles

O=C1C=CC2=C(OC/C=C(C)/CC/C=C(C)/C)C3=C(OC=C3)C=C2O1

Molecular Formula

C21H22O4

Molecular Weight

338.40

References & Citations

[1]Olguín-Reyes S, et al. Bergamottin is a competitive inhibitor of CYP1A1 and is antimutagenic in the Ames test. Food Chem Toxicol. 2012 Sep;50 (9) :3094-9.|[2]Wu HJ, et al. Bergamottin isolated from Citrus bergamia exerts in vitro and in vivo antitumor activity in lung adenocarcinoma through the induction of apoptosis, cell cycle arrest, mitochondrial membrane potential loss and inhibition of cell migration and invasion. Oncol Rep. 2016 Jul;36 (1) :324-32.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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