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IL-1RAcP/IL-1 R3, Mouse (HEK293, His)

IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process[1][2]. IL-1RAcP/IL-1 R3 Protein, Mouse (HEK293, His) is a recombinant mouse IL-1RAcP protein with a His tag at the C-terminus and is expressed in HEK293 cells.

Product Specifications

Product Name Alternative

IL-1RAcP/IL-1 R3 Protein, Mouse (HEK293, His), Mouse, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-1racp-il-1-r3-protein-mouse-347a-a-hek293-his.html

Molecular Formula

16180 (Gene_ID) Q61730-1 (S21-T367) (Accession)

Molecular Weight

Approximately 55-65 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]Neveu PJ, et al. Mechanisms of behavioral and neuroendocrine effects of interleukin-1 in mice. Ann N Y Acad Sci. 2000;917:175-85.|[2]Zarezadeh Mehrabadi A, et al. The roles of interleukin-1 receptor accessory protein in certain inflammatory conditions. Immunology. 2022 May;166 (1) :38-46.|[3]Wesche H, et al. The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases) . J Biol Chem. 1997 Mar 21;272 (12) :7727-31.

Shipping Conditions

Dry ice.

Scientific Category

Recombinant Proteins

Frequently Asked Questions

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