Oxelumab

Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L) . Oxelumab can be used for the research of asthma[1].

Product Specifications

CAS Number

[1186098-83-8]

Product Name Alternative

R 4930; huMAb OX 40L; Ro 49-89991

UNSPSC

12352203

Target

Interleukin Related

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/oxelumab.html

Purity

99.31

Solubility

10 mM in DMSO

Smiles

[Oxelumab]

Molecular Weight

(145.57 kDa)

References & Citations

[1]Youngblood BA, et al. AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice. Int Arch Allergy Immunol. 2019;180 (2) :91-102.|[2]Kweon S, et al. Expansion of Human NK Cells Using K562 Cells Expressing OX40 Ligand and Short Exposure to IL-21. Front Immunol. 2019 Apr 24;10:879.