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IRC-083864

Product Specifications

UNSPSC Description

IRC-083864 is an inhibitor of CDC25 phosphatase. IRC-083864 inhibits the activity of recombinant human full-length CDC25 phosphatase with an IC50 value of 23 nM. IRC-083864 inhibits cell viability with an IC50 value of 47 nM on the HL60 cell line[1].

Target Antigen

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/irc-083864.html

Smiles

O=C1C=C(C(C2=C1N=C(C3=C(F)C=CC(F)=C3)O2)=O)NCCCN(CCCNC4=CC(C5=C(C4=O)N=C(C)S5)=O)C

Molecular Weight

581.59

References & Citations

[1]Marie-Christine Brezak, et al. IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells. Int J Cancer. 2009 Mar 15;124(6):1449-56.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-123417/IRC-083864-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-123417/

Clinical Information

No Development Reported

CAS Number

1142057-18-8

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