IRC-083864

IRC-083864 is an inhibitor of CDC25 phosphatase. IRC-083864 inhibits the activity of recombinant human full-length CDC25 phosphatase with an IC50 value of 23 nM. IRC-083864 inhibits cell viability with an IC50 value of 47 nM on the HL60 cell line[1].

Product Specifications

CAS Number

[1142057-18-8]

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/irc-083864.html

Smiles

O=C1C=C(C(C2=C1N=C(C3=C(F)C=CC(F)=C3)O2)=O)NCCCN(CCCNC4=CC(C5=C(C4=O)N=C(C)S5)=O)C

Molecular Formula

C28H25F2N5O5S

Molecular Weight

581.59

References & Citations

[1]Marie-Christine Brezak, et al. IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells. Int J Cancer. 2009 Mar 15;124 (6) :1449-56.