IRC-083864
IRC-083864 is an inhibitor of CDC25 phosphatase. IRC-083864 inhibits the activity of recombinant human full-length CDC25 phosphatase with an IC50 value of 23 nM. IRC-083864 inhibits cell viability with an IC50 value of 47 nM on the HL60 cell line[1].
Product Specifications
CAS Number
[1142057-18-8]
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/irc-083864.html
Smiles
O=C1C=C(C(C2=C1N=C(C3=C(F)C=CC(F)=C3)O2)=O)NCCCN(CCCNC4=CC(C5=C(C4=O)N=C(C)S5)=O)C
Molecular Formula
C28H25F2N5O5S
Molecular Weight
581.59
References & Citations
[1]Marie-Christine Brezak, et al. IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells. Int J Cancer. 2009 Mar 15;124 (6) :1449-56.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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