YD-3
YD-3 is a platelet activation inhibitor. YD-3 inhibits Thrombine-induced rabbit platelets aggregation (IC50: 28.3 μM) and phosphoinositol production. In addition, YD-3 also inhibits Trypsin-induced platelet aggregation in human and rabbit with the IC50 of 38.1 μM and 5.7 μM, respectively, but does not affect the proteolytic activity of trypsin[1].
Product Specifications
CAS Number
[170632-41-4]
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/yd-3.html
Smiles
O=C(OCC)C1=CC=C(C2=NN(CC3=CC=CC=C3)C4=C2C=CC=C4)C=C1
Molecular Formula
C23H20N2O2
Molecular Weight
356.42
References & Citations
[1]Zhang Z, et al. Short day promotes gall swelling by a CONSTANS-FLOWERING LOCUS T pathway in Zizania latifolia. Plant J. 2024 Nov;120 (3) :1014-1031.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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