AAK1-IN-6
AAK1-IN-6 (Compound 23) is an inhibitor of AP-2-associated protein kinase 1 (AAK1, IC50 = 12 nM) with antiviral activity against the dengue virus (DNEV2, EC50 = 0.24 μM) and Venezuelan equine encephalitis virus (VEEV, EC50 = 0.30 μM) . AAK1-IN-6 can be utilized in antiviral research[1].
Product Specifications
CAS Number
3061058-16-7
UNSPSC
12352005
Target
AAK1; Dengue Virus
Type
Reference compound
Related Pathways
Anti-infection; Neuronal Signaling
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/aak1-in-6.html
Smiles
COC1=C(OC)C=C(C2=CN=C(NC=C3C4=CN=C(C5=CC=CC=C5)O4)C3=C2)C=C1
Molecular Formula
C24H19N3O3
Molecular Weight
397.43
References & Citations
[1]Ravi NP, et al. Synthesis of 3-heteroaryl-pyrrolo[2,3-b]pyridines as potent inhibitors of AP-2-associated protein kinase 1 (AAK1) with antiviral activity. Eur J Med Chem. 2024 Dec 15;280:116967.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC401966 20 µg
BAFF (TNFSF13B) (NM_006573) Human Over-expression Lysate
Sign In for Pricing
View Details 
