Salviolone
Product Specifications
UNSPSC Description
Salviolone is a natural diterpenoid derivative that can against melanoma cells. Salviolone exhibits a pleiotropic effect against melanoma by hampering cell cycle progression, STAT3 signaling, and malignant phenotype of A375 melanoma cells[1].
Target Antigen
STAT
Type
Natural Products
Related Pathways
JAK/STAT Signaling;Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/salviolone.html
Purity
99.61
Solubility
10 mM in DMSO
Smiles
O=C1C(C)=CC2=CC=C3C(C)(C)CCCC3=C2C=C1O
Molecular Weight
268.35
References & Citations
[1]Valentina Zanrè, et al. Salviolone from Salvia miltiorrhiza Roots Impairs Cell Cycle Progression, Colony Formation, and Metalloproteinase-2 Activity in A375 Melanoma Cells: Involvement of P21(Cip1/Waf1) Expression and STAT3 Phosphorylation. Int J Mol Sci. 2022 Jan 20;23(3):1121.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122506/Salviolone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122506/Salviolone-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
119400-86-1
Available Sizes
Curated Selection
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