Ferroptosis-IN-14

Ferroptosis-IN-14 (compund 36) exhibits the potent anti-ferroptosis activity with an EC50 value of 0.58 ± 0.02 μM and possessed excellent anti-ferroptosis activity, microsomal and plasma stability[1].

Product Specifications

UNSPSC

12352005

Target

Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ferroptosis-in-14.html

Smiles

O=C(/C=C/C1=CC(OC)=C(OC)C=C1OC)NC2=CC(C(NCC)=O)=CC=C2NC3CCCCC3

Molecular Formula

C27H35N3O5

Molecular Weight

481.58

References & Citations

[1]Zheng LY, et al. Synthesis and biological evaluation of ferrostatin-based diamide derivatives as new ferroptosis inhibitors. Bioorg Med Chem Lett. 2024 Nov 15;113:129974.