3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine
3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
565226-18-8
UNSPSC
12352005
Hazard Statement
H302-H315-H320-H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-5-di-o-acetyl-2-deoxy-2-fluoro-5-iodouridine.html
Solubility
10 mM in DMSO
Smiles
O=C(N1)N([C@H]2[C@H](F)[C@H](OC(C)=O)[C@@H](COC(C)=O)O2)C=C(I)C1=O
Molecular Formula
C13H14FIN2O7
Molecular Weight
456.16
Precautions
P264-P270-P330
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Fibronectin (HFN7.1), CF405S conjugate, 0.1mg/mL
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF405S conjugate, 0.1mg/mL
P21 / WAF1 (WA-1), CF740 conjugate, 0.1mg/mL
