WTAP Rabbit Polyclonal Antibody
Pre-mRNA-splicing regulator WTAP is a protein that in humans is encoded by the WTAP gene. The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in three transcript variants, two of which encode the same isoform. WTAP (gene) has been shown to interact with WT1.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
WTAP, KIAA0105
Swiss Prot
Q15007 Human, Q9ER69 Mouse,
Cellular Locus
Nucleus speckle, Nucleus, nucleoplasm, Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human WTAP aa 1-300 / 396.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Concentration
2 mg/mL
Dilution
WB: 1:1,000;IHC-P: 1:2,000;IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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