Asapiprant
Asapiprant is a potent and selective DP1 receptor antagonist with a Ki of 0.44 nM.
Product Specifications
CAS Number
932372-01-5
Product Name Alternative
S-555739
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Asapiprant.html
Purity
99.89
Solubility
DMSO : 11.11 mg/mL (ultrasonic)
Smiles
O=C(O)COC1=CC(N2CCN(S(=O)(C3=CC=C(OC(C)C)C=C3)=O)CC2)=CC=C1C4=NC=CO4
Molecular Formula
C24H27N3O7S
Molecular Weight
501.55
Precautions
H302, H315, H319, H335
References & Citations
[1]Takahashi G, et al. Effect of the potent and selective DP1 receptor antagonist, asapiprant (S-555739), in animal models of allergic rhinitis and allergic asthma. Eur J Pharmacol. 2015 Oct 15;765:15-23.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
DP
Available Sizes
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