EG1
EG1, a specific Pax2 inhibitor, directly binds the paired domain of Pax2 (Kd=1.35-1.5 μM) and inhibits Pax2-DNA interactions. EG1 can inhibit embryonic kidney development, a process directly dependent on Pax2 activity[1].
Product Specifications
CAS Number
[693241-54-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eg1.html
Purity
98.26
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=CC=C1NC(C2=CC=C(NC(C3=CC=CC=C3OC)=O)C=C2)=O
Molecular Formula
C22H18N2O5
Molecular Weight
390.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Grimley E, et al. Inhibition of Pax2 Transcription Activation with a Small Molecule that Targets the DNA Binding Domain. ACS Chem Biol. 2017;12 (3) :724-734.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9338301-03 5x 96 Well
Mouse Progressive ankylosis protein homolog, ANKH ELISA Kit
Ask
View Details