Photosensitizer Pc 4
Photosensitizer Pc 4 (NSC-676418) is a photosensitizer, which inhibits Plasmodium falciparum in dark or under red light by disturbing the protein/DNA synthesis, with an IC50 of 24 nM[1].
Product Specifications
CAS Number
135719-28-7
Product Name Alternative
NSC-676418
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/photosensitizer-pc-4.html
Smiles
C[Si](CCCN(C)C)(C)[O-][Si+4]12([N-]3C4=NC5=[N]1C(C6=CC=CC=C56)=NC7=C(C=CC=C8)C8=C9[N-]27)([N](C(C%10=CC=CC=C%11%10)=N9)=C%11N=C3C%12=CC=CC=C4%12)[OH-]
Molecular Formula
C39H35N9O2Si2
Molecular Weight
717.93
References & Citations
[1]Zhao XJ, et al., Structure-activity and mechanism studies on silicon phthalocyanines with Plasmodium falciparum in the dark and under red light. Photochem Photobiol. 1997 Aug;66 (2) :282-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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