Trichlormethiazide (Standard)

Trichlormethiazide (Standard) is the analytical standard of Trichlormethiazide. This product is intended for research and analytical applications. Trichlormethiazide is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model[1][2].

Product Specifications

CAS Number

[133-67-5]

UNSPSC

12352005

Hazard Statement

H317, H334

Target

Carbonic Anhydrase; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/trichlormethiazide-standard.html

Purity

98.11

Smiles

O=S(C1=C(Cl)C=C(C2=C1)NC(C(Cl)Cl)NS2(=O)=O)(N)=O

Molecular Formula

C8H8Cl3N3O4S2

Molecular Weight

380.66

Precautions

H317, H334

References & Citations

[1]K Yao, et al. Diuretic effects of KW-3902, a novel adenosine A1-receptor antagonist, in various models of acute renal failure in rats. Jpn J Pharmacol. 1994 Apr;64 (4) :281-8.|[2]J R Ballew, et al. Characterization of the antihypertensive effect of a thiazide diuretic in angiotensin II-induced hypertension. J Hypertens. 2001 Sep;19 (9) :1601-6.