Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan

Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is a drug-linker conjugate for ADC. Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan consists of Exatecan (HY-13631) and a linker. Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan can be used for synthesis of ADCs and for cancer research[1].

Product Specifications

CAS Number

[1599439-54-9]

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC; Topoisomerase

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-peg2-gly-gly-phe-gly-exatecan.html

Purity

98.62

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C=CC1=O)N1CCC(NCCOCCOCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCCCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C57H65FN10O15

Molecular Weight

1149.18

References & Citations

[1]Masuda Takeshi, et al. Preparation of antibody-drug conjugates for cancer therapy. Patent WO2014057687.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Camptothecins

Available Sizes

Curated Selection

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