Tienilic acid (Standard)

Tienilic acid (Standard) is the analytical standard of Tienilic acid. This product is intended for research and analytical applications. Tienilic acid (Ticrynafen; ANP 3624) acts as a diuretic hypotensive agent. However, Tienilic acid induces hepatotoxicity. Tienilic acid is converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro[1].

Product Specifications

CAS Number

[40180-04-9]

Product Name Alternative

Ticrynafen (Standard) ; ANP 3624 (Standard)

UNSPSC

12352005

Target

Cytochrome P450; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/tienilic-acid-standard.html

Smiles

O=C(O)COC1=CC=C(C(C2=CC=CS2)=O)C(Cl)=C1Cl

Molecular Formula

C13H8Cl2O4S

Molecular Weight

331.17

References & Citations

[1]Takayoshi Nishiya, et al. Involvement of cytochrome P450-mediated metabolism in tienilic acid hepatotoxicity in rats. Toxicol Lett. 2008 Dec 15;183 (1-3) :81-9.