Tienilic acid (Standard)
Tienilic acid (Standard) is the analytical standard of Tienilic acid. This product is intended for research and analytical applications. Tienilic acid (Ticrynafen; ANP 3624) acts as a diuretic hypotensive agent. However, Tienilic acid induces hepatotoxicity. Tienilic acid is converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro[1].
Product Specifications
CAS Number
[40180-04-9]
Product Name Alternative
Ticrynafen (Standard) ; ANP 3624 (Standard)
UNSPSC
12352005
Target
Cytochrome P450; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tienilic-acid-standard.html
Smiles
O=C(O)COC1=CC=C(C(C2=CC=CS2)=O)C(Cl)=C1Cl
Molecular Formula
C13H8Cl2O4S
Molecular Weight
331.17
References & Citations
[1]Takayoshi Nishiya, et al. Involvement of cytochrome P450-mediated metabolism in tienilic acid hepatotoxicity in rats. Toxicol Lett. 2008 Dec 15;183 (1-3) :81-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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