ARN726
Product Specifications
UNSPSC Description
ARN726 is a potent NAAA (N-acylethanolamine acid amidase) inhibitor with an IC50 of 0.073 µM. ARN726 decreases alcohol self-administration in a dose-dependent manner[1][2].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/arn726.html
Purity
95.00
Solubility
DMSO : 36.67 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(OCCCCC1CCCCC1)N[C@@H]2C(NC2)=O
Molecular Weight
268.35
References & Citations
[1]Fotio Y, et al. N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats. Psychopharmacology (Berl). 2021 Jan;238(1):249-258.|[2]Petracca R, et al. Novel activity-based probes for N-acylethanolamine acid amidase. Chem Commun (Camb). 2017 Aug 22;53(86):11810-11813.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124597/ARN726-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124597/ARN726-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1628343-77-0
Available Sizes
Curated Selection
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