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ARN726

ARN726 is a potent NAAA (N-acylethanolamine acid amidase) inhibitor with an IC50 of 0.073 µM. ARN726 decreases alcohol self-administration in a dose-dependent manner[1][2].

Product Specifications

CAS Number

[1628343-77-0]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/arn726.html

Purity

95.00

Solubility

DMSO : 36.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(OCCCCC1CCCCC1)N[C@@H]2C(NC2)=O

Molecular Formula

C14H24N2O3

Molecular Weight

268.35

References & Citations

[1]Fotio Y, et al. N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats. Psychopharmacology (Berl) . 2021 Jan;238 (1) :249-258.|[2]Petracca R, et al. Novel activity-based probes for N-acylethanolamine acid amidase. Chem Commun (Camb) . 2017 Aug 22;53 (86) :11810-11813.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-124597/ARN726-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-124597/ARN726-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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