What is the catalog number for Ochratoxin B-13C20?

The catalog number for Ochratoxin B-13C20 is HY-N6786S.

What sizes are available for Ochratoxin B-13C20?

Ochratoxin B-13C20 is available in the following size(s): 12 μg (25.69 μM x 1.2 mL in Acetonitrile).

Is Ochratoxin B-13C20 in stock?

Ochratoxin B-13C20 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ochratoxin B-13C20?

Ochratoxin B-13C20 is manufactured by QuantiMol.

What is the estimated delivery time for Ochratoxin B-13C20?

Estimated delivery time for Ochratoxin B-13C20 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ochratoxin B-13C20?

The safety data sheet for Ochratoxin B-13C20 is available here: http://file.medchemexpress.com/batch_PDF/HY-N6786S/.

Ochratoxin B-13C20

Ochratoxin B-13C20 is 13C-labeled Ochratoxin B. Ochratoxin B is an orally active secondary metabolite of Aspergillus ochraceus and non-chlorinated analog of the mycotoxin Ochratoxin A. Ochratoxin B reduces the toxic effects of Ochratoxin A (HY-N6788). Ochratoxin B inhibits cell division. Ochratoxin B causes craniofacial malformations in Xenopus laevis embryos[1][2][3][4][5][6][7].

Product Specifications

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Cancer-programmed cell death

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ochratoxin-b-13c20.html

Concentration

25.69 μM * 1.2 mL in Acetonitrile

Solubility

10 mM in DMSO

Smiles

O=[13C]1O[13C@@H]([13CH3])[13CH2][13C]2=[13C]1[13C](O)=[13C]([13C](N[13C@H]([13C](O)=O)[13CH2][13C]3=[13CH][13CH]=[13CH][13CH]=[13CH]3)=O)[13CH]=[13CH]2

Molecular Formula

13C20H19NO6

Molecular Weight

389.22

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-220.|[2]Knasmüller S, et al. Structurally related mycotoxins ochratoxin A, ochratoxin B, and citrinin differ in their genotoxic activities and in their mode of action in human-derived liver (HepG2) cells: implications for risk assessment. Nutr Cancer. 2004;50 (2) :190-7.|[3]O'Brien E, et al. Investigation of the teratogenic potential of ochratoxin A and B using the FETAX system. Birth Defects Res B Dev Reprod Toxicol. 2005 Oct;74 (5) :417-23.|[4]Dietrich DR, et al. Species- and sex-specific renal cytotoxicity of ochratoxin A and B in vitro. Exp Toxicol Pathol. 2001 Jun;53 (2-3) :215-25.|[5]Csenki Z, et al. The individual and combined effects of ochratoxin A with citrinin and their metabolites (ochratoxin B, ochratoxin C, and dihydrocitrinone) on 2D/3D cell cultures, and zebrafish embryo models. Food Chem Toxicol. 2021 Dec;158:112674.|[6]Mally A, et al. Biotransformation and nephrotoxicity of ochratoxin B in rats. Toxicol Appl Pharmacol. 2005 Aug 1;206 (1) :43-53.|[7]Størmer FC, et al. Metabolism of ochratoxin B and its possible effects upon the metabolism and toxicity of ochratoxin A in rats. Appl Environ Microbiol. 1985 May;49 (5) :1108-12.